Despite its name, pancreatic neuroendocrine tumors are rare. These tumors develop in the islet cells and hormone-making organs in the pancreas. The pancreas is a small organ about six inches long, with a head, body, and tail. It is located behind the stomach and just in front of the spine. If one of these tumors is causing your symptoms, it is important to see a doctor immediately.
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Besides stomach pain, patients may also experience nausea, vomiting, and abdominal swelling. Some tumors produce a substance called VIP that can cause diarrhea, which can get worse over time. Diarrhea is the most common symptom in people with intestinal tumors. Other symptoms include flushing, nausea, muscle cramps, and weakness. People with these tumors often experience a low stomach acid level, making it difficult to digest food.
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Treatment options for pancreatic neuroendocrine tumors vary. They range from surgery to radiation therapy. Surgery is the usual treatment for pancreatic neuroendocrine tumors. Some tumors spread to the bones, while others remain within the pancreas. In the case of pancreatic cancer, surgery may be the only option. The surgeon will remove the tumor as well as surrounding lymph nodes.
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In addition to these symptoms, you may also experience high blood sugar, frequent urination, and weight loss. Diarrhea, which is a common symptom, can also cause weakness, muscle cramps, and a yellowing of the skin and eyes. Diarrhea can be painful and a rash may occur. Diarrhea may also lead to indigestion and constipation.
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Early detection and treatment is important for a good outcome. Surgery may be the best way to prevent a tumor from growing. Surgery removes the tumor, but the patient can experience other symptoms. Sometimes, tumors will spread to other organs, like the liver, or may have metastases in other organs. However, if detected early enough, treatment can significantly increase the chance of survival.
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There are many symptoms of a pancreatic neuroendocrine tumor. However, the symptoms you may be experiencing are not due to this cancer, but instead may be related to another health issue. Patients with these symptoms should see a doctor to confirm whether they are due to a pancreatic neuroendocrine tumour. And remember that the symptoms of a pancreatic neuroendocrine tumor will differ depending on the type of tumour.
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In most cases, the pancreatic neuroendocrine tumors start in cells known as endocrine. These cells produce hormones for digestion and blood sugar regulation. They can also form tumors in the exocrine cells. In the latter case, the cancer may move throughout the body, including the lymph vessels. In some cases, patients may have diarrhea or low blood sugar. In severe cases, patients may also experience intermittent or severe diarrhea.
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Although 90% of pancreatic neuroendocrine tumors occur sporadically, there is no known cause, and there is no way to prevent this disease. Although there is no specific cure, three hereditary syndromes have been linked to the development of this cancer. If you have one of these syndromes, your healthcare provider can recommend genetic testing and screening for pNET without symptoms. As with all cancers, the prognosis varies.
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Pancreatic neuroendocrine tumors are diagnosed during routine checkups. Surgery and chemotherapy are common treatments, and radiation therapy is also used for the control of symptoms in metastatic tumors. Treatment for pancreatic neuroendocrine tumors involves a multidisciplinary approach from endocrinologists and endocrine surgeons to radiologists and nuclear medicine specialists. Patients with pancreatic neuroendocrine tumors should seek diagnosis as early as possible.
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Treatment for pancreatic neuroendocrine tumors depends on the stage of the disease and its grade. Surgery is the preferred treatment option for resectable pancreatic NETs, but it is not always recommended in advanced staged cases. Patients with pancreatic NETs are often treated with chemotherapy, but major resections are associated with a high risk of complications.
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Patients with a tumour may have symptoms such as indigestion or vomiting. This may be a result of excess stomach acid produced by the tumour. Patients may also experience gastric pain or stomach ulcers, and these can be life-threatening. Patients with symptoms such as nausea, vomiting, or bloating should consult their doctor. And if symptoms don't improve, it may be a sign of cancer.
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Because pancreatic neuroendocrine tumors are rare, they may be missed. Only about 1,000 people are diagnosed with pancreatic neuroendocrine tumors in the United States each year. Insulininoma is the most common type of pancreatic cancer and is only 2 cm wide. Non-functioning pancreatic neuroendocrine tumors are much rarer. They start in cells that produce different hormones such as insulin and glucagon. There are two different types of pancreatic NET: non-functioning and functioning.
