Symptoms of Pancreatic Neuroendocrine Tumor (PNET) vary between patients. Symptoms may be absent or similar to symptoms caused by other health problems. However, pancreatic NETs can produce high amounts of certain hormones in the blood. These abnormal hormones can result in low blood sugar, which can cause constipation and fatigue. Pancreatic NETs are typically found during routine tests for other ailments.
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These tumors develop in the endocrine cells of the pancreas, which produce hormones for digestion and blood sugar regulation. The endocrine pancreas is made up of approximately 100,000 endocrine cells called islets. This tissue produces insulin and other hormones that regulate blood sugar levels. This disease can cause symptoms like fast heartbeat, fatigue, and blurred vision.
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Most pancreatic NETs are non-functional and do not cause symptoms due to excessive hormone secretion. Patients are usually diagnosed by accident during imaging tests for another medical condition. However, some patients may experience upper abdominal discomfort from large tumors because of their compression of surrounding structures. Non-functional neuroendocrine tumors can be surgically removed, although the prognosis is less favorable than that of pancreatic adenocarcinoma.
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Although Pancreatic NETs are rare, they may spread to other parts of the body. A pancreatic NET may enlarge the liver. This can cause an enlarged liver and can affect liver function. Other symptoms include vomiting, diarrhea, and muscle cramps. Some patients also experience flushing and decreased stomach acid, which can interfere with digestion.
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However, there is no definitive test for the presence of Pancreatic Neuroendocrine Tumors.
The most common pancreatic neuroendocrine tumor is insulinoma. Most insulinomas are small and behave benignly. Insulin regulates blood sugar levels by promoting the movement of glucose into cells, fat cells, and the liver. In some cases, insulinomas can cause low blood sugar, a condition known as hypoglycemia. In extreme cases, hypoglycemia can result in seizures or even coma.
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If the symptoms are accompanied by pain, an imaging test can help determine the diagnosis. If a pancreatic neuroendocrine tumor is located in the pancreas, it may be malignant. However, there is no definitive treatment for this disease. The symptoms of pancreatic neuroendocrine tumors can mimic the symptoms of other illnesses. Symptoms of pancreatic neuroendocrine tumors are similar to those of other diseases and are difficult to identify.
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A diagnosis of Pancreatic Neuroendocrine Tumor is a key step to the treatment process. It is important to identify the symptoms early to avoid complications and maximize your chances of a cure. If you suspect that you have PNETs, contact your physician immediately. You may be able to avoid the risks associated with pancreatic cancer by following some guidelines.
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You may want to consult with a doctor who specializes in pancreatic neuroendocrine tumors.
While pancreatic neuroendocrine tumors are rare, their prevalence has increased in the past decade. Recent advances in diagnosis and treatment have increased the diagnosed incidence of pancreatic NETs. Experts from various medical fields work together in multidisciplinary teams to better diagnose and treat patients. These professionals are essential in diagnosing and treating patients with pancreatic neuroendocrine tumors. You may even be suffering from the symptoms of a PNET.
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Treatment for these rare cancers depends on whether the tumor is growing in a specific location. If not, it may have spread to the liver and bone. Treatment with somatostatin analogues is another treatment option. Treatment is based on the size and location of the tumor and whether the patient's tumor can be removed. However, if you have NETs that have spread beyond the pancreas, treatment may not be as effective.
