Myelodysplastic syndromes symptoms are characterized by low levels of white blood cells, recurrent infections, and a weak immune system. People who have this condition should avoid exposure to other people with the disease to help protect their immune system. Heavy metals have been linked to myelodysplastic syndromes. Exposure to heavy metals can also increase the risk of developing the disorder. Bleeding is also one of the symptoms, as the body does not produce enough platelets to stop clotting.
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There are three subtypes of myelodysplastic syndromes. Symptoms and treatments vary between these types. Most cases are de novo MDS. Treatment-related MDS is more difficult to treat than de novo MDS. Most people with the condition have de novo MDS, but a small number have the disease because of therapy. The symptoms of treatment-related MDS vary, depending on the underlying cause.
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MDS-EB is another subtype of this disease. This type affects two types of blood cells and has fewer immature cells than the other subtypes. It is caused by a genetic mutation. The del (5q) chromosome causes the bone marrow to produce less mature blood cells than normal. Because of this, patients with this type of disease will have fewer red and white blood cells than normal.
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A number of symptoms of MDS include fatigue, anemia, and refractory anemia. Treatment for myelodysplastic syndromes depends on the type of disease and its complications. In some cases, treatment may include chemotherapy or bone marrow transplant. However, this is only a last resort. Because patients with this condition may not develop early symptoms, early diagnosis is necessary to manage the condition.
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Myelodysplastic syndromes are disorders in which the bone marrow fails to produce sufficient numbers of healthy blood cells. Those affected by this condition may experience fatigue, shortness of breath, and other symptoms. The severity of symptoms can vary from person to person. However, the disease may have progressive complications, such as anemia and bone marrow failure. This disease can be life threatening.
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Myelodysplastic syndromes are progressive, and in some cases can progress to leukemia. If left untreated, this disease can progress to acute myeloid leukemia. If left untreated, myelodysplastic syndromes may lead to acute myeloid leukemia in about one-third of patients. Symptoms of MDS can vary based on the type of disease and the exposure to substances.
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Myelodysplastic syndromes symptoms occur with an abnormality of the chromosomes in bone marrow. The result is that red blood cell levels are abnormally low. While platelets and white blood cells are normal, blast cells are abnormally high. Affected patients with RAEB-2 do not develop leukemia. Consequently, patients with this condition are usually well-advanced and have a long life expectancy.
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Despite the fact that it is considered a chronic disease, myelodysplastic syndromes can affect people of all ages. Though most cases of MDS occur in the elderly, children are rarely diagnosed with the disease. In contrast, primary MDS is the most common type of myelodysplastic syndrome, with no known cause. Secondary MDS can occur after exposure to certain types of radiation therapy or chemotherapy. The DNA damage may take years to turn into myelodysplasia.
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Treatment for myelodysplastic syndromes varies in intensity and type. Some cases are inherited, and genetic testing and genetic counseling may be necessary to determine your risk. Genetic testing and counseling may be the best option if you suspect you have a family history of the disease. This can help you determine what to do to improve your chances of living a healthy life. And once you've received proper diagnosis, you'll need to change your lifestyle to live a normal life.
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Myelodysplastic syndromes are a common cancer in the elderly. While the incidence of MDS in this age group has increased, it is also more common in males. Approximately 22 to 45 per 100,000 people older than 70 are diagnosed each year. With increased awareness of the disease and the number of elderly people in the general population, the number of cases is expected to grow. A lack of reporting of mild cytopenias, however, makes it difficult to determine the exact frequency of the disorder.
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Treatment for MDS is based on the type of MDS and its severity. Patients with MDS may undergo chemotherapy as a part of their treatment, which is used to prevent degeneration of their bone marrow. Patients with therapy-related MDS are at greater risk for developing acute myeloid leukemia. Treatment options are dependent on the disease and the patient's overall health and ability to perform daily tasks.
