Myelodysplastic syndromes (MDS) are disorders of the blood that cause low counts of healthy blood cells. In mild forms, these symptoms may include anemia, low white blood count, or platelets. About 10% to 20% of diagnosed cases progress to acute myeloid leukemia. Blood contains three basic types: red blood cells, white blood cells, and platelets. Normally, these blood cells are produced in the bone marrow and flow through the blood.
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Treatment for patients with myelodysplastic syndromes varies widely, and depends on the type of cells that are damaged. In general, the aim of treatment is to control the disease and ease symptoms. Drug therapy, blood transfusions, and stem cell transplants are some common treatments. In severe cases, chemotherapy can be used to cure the disease. In such cases, treatment is often combined with a stem cell transplant.
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Most patients with RCMD do not develop leukemia. But about 10% of them develop a refractory form of the disease. In such cases, the blood cells are abnormally low in red blood cells. In addition, white blood cells are normally normal. Platelets can be increased as well. Fortunately, patients with RCMD don't progress to leukemia, and their prognosis is good.
If you suspect that you may have MDS, your doctor will likely test for a genetic mutation that causes your condition. In rare cases, MDS can progress to leukemia if left untreated.
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Although the cause of de novo MDS is unknown, lifestyle factors have been associated with it. While MDS is rare, it may develop after cancer therapy, radiation therapy, or chemotherapy. The good news is that treatment for myelodysplastic syndromes is still available.
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Some common symptoms of myelodysplastic syndromes include low red blood cell counts, low platelet count, and anemia. A physician can perform a bone marrow test to confirm the diagnosis. The symptoms may also include shortness of breath and fatigue. To diagnose the disorder, a doctor will order a bone marrow test to determine the specific mutation. In some cases, the symptoms will be quite severe, but these tests should be performed only after you have received a blood transfusion.
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Patients with myelodysplastic syndromes are at an increased risk of contracting infections. Frequent infections, fevers, and repeated sinus and lung infections are common in patients with MDS. Their immune system may be weakened and ineffective in fighting infections. They may also develop skin infections. If the condition continues, patients may develop a range of skin problems, including infections. The symptoms of myelodysplastic syndromes may include infections in their skin and in their bones.
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Fortunately, treatment can help slow the progression of Myelodysplastic Syndromes and improve the symptoms. A doctor will give you a diagnosis of Myelodysplastic Syndromes and prescribe a course of treatment. Patients can expect their symptoms to improve gradually over time. Even though the disease will never go away, treatments can alleviate symptoms. If you do have anemia, it's important to seek treatment right away.
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The best way to diagnose this disorder is to undergo blood tests. Blood tests will determine the severity of your condition and help you find the most appropriate treatment. In severe cases, the condition may progress to acute myeloid leukemia. Although early symptoms are rare, the disease can cause severe complications, including amputation. In most cases, treatment is focused on improving symptoms and preventing complications. When symptoms do occur, they will be accompanied by signs and symptoms of MDS.
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Most MDS patients are anemic at the time of diagnosis. Low hemoglobin and hematocrit, the proteins responsible for carrying oxygen throughout the body, can cause fatigue. Patients may also experience bruising and bleeding easily. Anemia may also result in pale skin and frequent infections. This disease may also cause bone and joint pain. It can also cause chronic fatigue, and it may even result in death.
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Myelodysplastic Syndromes symptomatology is a field that is rapidly evolving. It may be difficult to find a doctor who understands MDS. But the right medical treatment is available for individuals with this disease. Several approved treatments are now available to treat the symptoms and slow the progression of the disease. In some cases, medications may be necessary. If your symptoms do not improve, your doctor may suggest a course of treatment.
