Myelodysplastic syndromes, or MDS, are disorders of the blood cells. The disorder causes too few healthy blood cells to grow properly and can result in low blood counts. Some mild forms of the disorder may cause anemia and low white blood cell counts. About 10% to 20% of diagnosed cases progress to acute myeloid leukemia. Normal blood is composed of three types of cells: red blood cells, white blood cells, and platelets. They flow through the bloodstream and the bone marrow, where they are produced.
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Treatment for myelodysplastic syndromes varies according to the type and severity of the disease. Supportive care and drug therapy are frequently used to ease symptoms and improve quality of life. In rare cases, aggressive chemotherapy is used to cure the disease and can be followed by stem cell transplant. However, these therapies can have severe side effects and may require a long-term course of follow-up care.
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People with this disorder are susceptible to infections due to their low platelet count and low white blood cell count. The condition is also associated with a weak immune system, making it important to limit exposure to sick people. Heavy metals such as lead and mercury can trigger symptoms of myelodysplastic syndrome. Patients with this disorder are often exposed to toxic chemicals such as these. If they are exposed to these chemicals, their immune systems may not be able to properly fight infection.
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Myelodysplastic syndromes are often classified into different subtypes based on the type of blood cells affected. Some individuals have only one blood cell type, while others have low numbers of several different types. Others have reduced numbers of mature red blood cells. For the most accurate diagnosis, a complete blood count with differential is recommended. Symptoms may include anemia, bone marrow failure, and anemia.
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Early diagnosis of myelodysplastic syndromes is difficult due to the fact that symptoms are often not noticeable until later stages of the disease. Treatments for myelodysplastic syndromes focus on managing complications and reducing the risk of the disease spreading to other parts of the body. In the worst case scenario, the disease could progress to the point where a bone marrow transplant is necessary.
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Myelodysplastic syndromes are usually treated with one of two drugs: azacitidine and decitabine. These drugs are used to increase the production of mature red blood cells. These two drugs can reduce the number of blast cells in the bone marrow and may slow the progression of myelodysplastic syndromes to leukemia. People with high blast counts in their bone marrow may also be treated with chemotherapy.
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Patients with Myelodysplastic Syndromes are at risk of anemia and infection. Treatment for this disorder can slow disease progression and ease symptoms. If symptoms persist, a doctor may prescribe a medication. Myelodysplastic Syndromes symptoms vary from patient to patient. Nevertheless, the best way to manage these symptoms is to seek treatment from a specialized doctor. When the condition is advanced, treatment for myelodysplastic syndromes can help manage the symptoms and slow down the disease progression.
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One of the most common types of MDS is refractory cytopenia with ring sideroblasts. These patients experience anemia. During their lifetime, they may develop acute myeloid leukemia and die. Rarely, RARS degenerates into acute myeloid leukemia. Most patients with MDS do not develop this leukemia, but they can live for decades.
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In some people, exposure to heavy metals, smoking, and age can increase the risk of developing MDS. Another form of MDS is de novo, where the cause is unknown. A minority of MDS patients have MDS due to exposure to chemotherapy or radiation. It is rare for a child to develop MDS, but if they do, they should seek treatment. Myelodysplastic syndromes symptoms can be difficult to recognize, but they can occur.
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While Myelodysplastic syndromes are often mistaken for leukemia, they are a form of cancer. As with any cancer, treatment is necessary depending on the type of MDS. It is important to know the symptoms associated with MDS to make the proper diagnosis. The symptoms of MDS can vary widely from one patient to another, so knowing your specific type will be critical to ensuring the best outcome.
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MDS patients often experience anemia when they are first diagnosed. Anemia, a condition in which blood cells cannot produce enough of the essential proteins that keep the body functioning, can result in fatigue. Aplastic anemia may result in chronic tiredness, pallor, and weakness. However, in the worst case, anemia can lead to life-threatening complications. There are several different symptoms of anemia and they vary from one person to another.
