Some symptoms of mycosis fungoides are similar to other common skin problems, such as eczema or psoriasis. To rule out cancer, doctors use biopsy to identify the cause of the symptoms. In cases where the disease is confined to the skin, doctors can apply creams or gels that contain chemotherapy drugs to alleviate itch and reduce inflammation. Some people develop tumors on their skin, but this is unusual and usually not fatal.
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Patients with mycosis fungoides may develop plaques without clinical lymphadenopathy. However, sometimes tumors form from plaques without lymphadenopathy, and the plaques may be ulcerated. Some patients may experience rapid, multifocal development of tumors without patches or plaques, which may be primary pleomorphic lymphomas. However, if the symptoms persist after several months, it is time to seek medical attention.
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The signs and symptoms of mycosis fungoides vary from patient to patient, but the main symptoms are scaly, flat, red, or pink patches on the skin. These patches can be itchy or ulcerated. They occur in areas of the body with little exposure to sunlight, and the condition can be misdiagnosed as a skin infection or another disease. In some people, light patches may develop, which may be a sign of another condition, such as a fungal infection.
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Mycosis fungoides is a type of cancer that attacks white blood cells. When the disease is left untreated, the disease will continue to worsen. Twenty percent of people with this disease will develop a malignant lymphoma and spread to different organs. In late stage, the immune system of patients with mycosis fungoides will fail and the disease may even lead to death. Staphylococcus aureus and Psudomonas aeruginosa are known to spread the disease.
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Some symptoms of mycosis fungoides may be more severe. People with SS may have a rash that covers most or all of their skin. A red rash that is scaly and itchy, called generalized erythroderma, may be present. Sezary cells may be found in the lymph nodes and blood of people with SS. It can be difficult to diagnose and treat mycosis fungoides because the person has a weakened immune system.
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Aside from the above-mentioned treatments, patients may benefit from photopheresis therapy. This treatment uses ultraviolet light to kill cancer cells within the blood. It's similar to giving blood. The T-cells are removed, treated with a drug, and then re-mixed with the patient's blood. However, photopheresis therapy is often used for advanced cases of mycosis fungoides because it boosts the immune system against other cancer cells. However, it's important to note that photopheresis can result in worsening dryness. For this reason, it is important to take showers with lukewarm water, and avoid prolonged hot baths. In addition, avoid rubbing the affected area as this can cause the dryness to worsen.
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Mycosis fungoides is a type of cancer that affects the skin. It is caused by cancerous T-cells in the lymph system, which are white blood cells that produce antibodies that fight infections. It typically develops in people over the age of 50, but children can also be affected. If the symptoms of mycosis fungoides persist for years, a doctor may recommend chemotherapy. However, this type of treatment is often unsuccessful, and the patient's condition may worsen over time.
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Patients with mycosis fungoides may develop a rash that consists of patches, plaques, or tumors. A median period of time between the onset of symptoms and diagnosis is 6 years. Early lesions may be nonspecific and require biopsy to confirm a diagnosis. Biopsies of the affected areas may be performed to differentiate mycosis fungoides from other skin conditions.
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Fortunately, immunotherapy treatments are increasingly common. Mogamulizumab, a monoclonal antibody, has been approved by the FDA for use in adult patients with relapsed or refractory mycosis fungoides, or Sezary syndrome. A recent study suggests that the treatment can reduce the risk of side effects. Patients with mild symptoms can live with their disease for up to a decade.
